-->The parasympathetic innervation originates in the second to fourth sacral segments. The cholinergic postganglionic fibers supply both the bladder and smooth muscle sphincter. ==In parasympathetic innervation, acetylcholine and nicotinic receptors mediate pre- to postganglionic transmission, while acetylcholine and M2 muscarinic receptors mediate the postganglionic neuron-smooth muscle transmission
-->The sympathetic nerves originate at T10-L2. The noradrenergic postganglionic fibers innervate the smooth muscles of the bladder base, internal sphincter, and proximal urethra. ==In sympathetic nerves, noradrenaline can act on the beta-2-adrenoreceptors to relax the detrusor or the alpha-1 receptors to contract the bladder neck and the external sphincter.
-->Somatic motor innervation originates in S2-3 and travels to the striated urethral sphincter via the pudendal nerve.
-->The parasympathetic innervation originates in the second to fourth sacral segments. The cholinergic postganglionic fibers supply both the bladder and smooth muscle sphincter.
ReplyDelete==In parasympathetic innervation, acetylcholine and nicotinic receptors mediate pre- to postganglionic transmission, while acetylcholine and M2 muscarinic receptors mediate the postganglionic neuron-smooth muscle transmission
-->The sympathetic nerves originate at T10-L2. The noradrenergic postganglionic fibers innervate the smooth muscles of the bladder base, internal sphincter, and proximal urethra.
==In sympathetic nerves, noradrenaline can act on the beta-2-adrenoreceptors to relax the detrusor or the alpha-1 receptors to contract the bladder neck and the external sphincter.
-->Somatic motor innervation originates in S2-3 and travels to the striated urethral sphincter via the pudendal nerve.
Source - Smith's Urology
ReplyDelete